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Computational Biologist to design and execute phylogenetic/statistical analyses to study viral evolution (primarily HIV-1).

The Henry M Jackson Foundation for the Advancement of Military Medicine
(HJF) is seeking a Computational Biologist who designs and executes
phylogenetic and statistical analyses to study viral evolution. Provides
analytic support and collaborative assistance to investigators and
personnel. Remote options are available for this opening.

This position will be in support of the Viral Genomics Section and
Systems Serology Core under the direction of Dr. Morgane Rolland in the
US Military HIV Research Program. The candidate will be part of a diverse
team of biologists, clinicians and statisticians working on a range of
questions related to vaccine and cure research focusing on HIV and other
emerging infectious diseases such as Ebola, Zika or SARS-CoV-2. The
Rolland Lab generates and analyzes molecular sequence data to infer
evolutionary and population dynamic processes. We also profile antibody
responses to various pathogens such as HIV, flaviviruses, filoviruses
or coronaviruses.

Integrated analyses aim to characterize the interplay between evolutionary
dynamics and the host immune pressure in the context of natural infection
or following vaccination.

For more information:
https://www.hivresearch.org/lab/viral-genomics-section-systems-serology-core-laboratory
https://www.hivresearch.org/our-team/morgane-rolland-phd

Responsibilities
Develops new sequence analysis pipelines and procedures. Performs
phylogenetic, phylogeographic and modeling studies. Conducts
data???driven and hypothesis-directed genetics research. Assists with
the report of experimental results for publication in technical and
peer-reviewed journals. Contributes and edits data, text, and figures
in program publications. May supervise junior informatics staff.

Required Knowledge, Skills and Abilities
Research experience in computational genomics or biostatistics
demonstrated through publications; programming ability in (R or other
statistical language). Scripting language (Perl, Python, or comparable),
and (C/C++, Java or comparable language). Experience with next-generation
sequencing analysis i.e. alignment, quality assessment, variant detection,
statistical inference. Preferred experience with trait association
analysis such as Plink, glm. Experience with pipeline development and
implementation on compute clusters. Experience with power calculations
and study design. Demonstrated ability to work effectively as part
of a team in a deadline-driven environment. Good communication and
analytical skills. Supervisory Responsibilities

Work Environment
This position will take place primarily in a laboratory setting or
remotely.

Education and Experience
Master's Degree required, Doctoral degree preferred within Computational
Biology, Bioinformatics, Biostatistics, Computer Science or related
discipline Minimum of 0-2 years experience required

All HJF employees are required to be fully vaccinated against
COVID-19. Proof of vaccination or an approved religious or medical
accommodation will be required.

Contact: Morgane Rolland, mrolland@hivresearch.org

Type
Postdoc
Institution
Henry Jackson Foundation for the Advancement of Military Medicine
City
Silver Spring/Remote
Country
USA
Closing date
November 13th, 2022
Posted on
October 13th, 2022 19:23
Last updated
October 13th, 2022 19:23
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