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Comparing drug-resistant tuberculosis treatment choices

With an estimated 30% of AMR-related deaths a result of
drug-resistant TB globally, the choice of drugs used for
treatment of TB disease is of the utmost importance.
However, many cases of TB disease are treated without a
complete knowledge of the resistance profile of the
underlying bacteria, due to a lack of availability of diagnostic

The aim of this project will be to improve the decision-making
around such empiric therapy, by using mathematical
modelling and quantitative methods to balance and assess
the factors contributing to the decision-making process. The
intention will be to inform development of treatment
guidelines, to ensure that treatment decisions are based on a
comprehensive consideration of evidence.

The outputs from this project will translate directly into clinical
care impact and can support optimised antibiotic usage for
TB and other important pathogens globally.

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PhD position
London School of Hygiene and Tropical Medicine
Closing date
January 26th, 2021
Posted on
November 19th, 2021 10:07
Last updated
November 24th, 2021 10:08