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Combine extremely high-throughput serology all human pathogens with epidemiological and mathematical models of disease dynamics.

The Mina lab focuses on cross-species and cross-scale dynamics of infectious diseases and vaccines utilizing combinations of high-throughput serological techniques and ecological modeling.

The Postdoctoral Researcher will have an opportunity to work on numerous projects that include combinations of extremely high-throughput serology, ecological modeling of infectious diseases, and linking immunology to pathogen dynamics and population outcomes across scales: from individual immunological consequences and responses to vaccines and infections, to modeling landscapes of infectious disease dynamics across space, time, ages, etc.

Potential projects include:
Computational +/- lab component
• Using high-complexity serological data (10000’s of antibody responses per individual) to help elucidate the heterologous effects of vaccines and infections at the immunological and population levels.
• Improve understandings of early immune development, how immunity develops from birth onward to elderly, and how this interacts with the myriad exposures to pathogens throughout life.
• Evaluating the role of measles vaccines to reduce morbidity and mortality due to all other infections.
• Development of novel methods for the detection and reconstruction of ongoing or past epidemics using high-throughput serological data.
• Estimating global landscapes of infectious diseases from age and geographically structured serological data.
• Linking vaccines and infectious disease dynamics to long-term economic and human-capital gains.

Lab bench +/- computational
• Development of novel accessible high-throughput serological assays through incorporation of nanopore sequencing and other portable technologies, for use in public health settings.
• Considerable opportunity for advancing new technologies and for collaboration with Steve Elledge’s lab at Harvard Medical School)

Harvard School of Public Health
Closing date
December 31st, 2019
Posted on
September 10th, 2019 08:39
Last updated
September 10th, 2019 08:39